Our immune system has a dark side: It’s supposed to fight off invaders to keep us healthy. But sometimes it turns traitor and attacks our own cells and tissues. What are called autoimmune diseases can ...

Neuroimmunology has rapidly evolved as a critical field for understanding how inflammatory and immune processes shape the pathophysiology of brain ...

Immune thrombocytopenia (ITP) is a chronic autoimmune disorder associated with platelet destruction and increased bleeding risk, substantial economic burden, and impairment of health-related quality ...

Sergio A. Giralt, MD, discusses how the pathophysiology of chronic graft-vs-host disease involves complex immune dysregulation, with CSF1R playing a crucial role in driving the differentiation of ...

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of type-1 diabetes, hepatitis, multiple sclerosis, shows a new study in mice. In these autoimmune diseases ...

Monoclonal antibodies can block a key immune-related protein that drives the spread of brain cell damage in Parkinson's ...

Imagine waking up already feeling drained, as if you never slept at all. Or noticing that your hands feel inexplicably stiff and swollen, making simple tasks like opening a jar or even typing feel ...

Autoimmune diseases share the same core pathology despite their differing clinical manifestations: dysregulated B and T cell activity. B cells contribute to disease progression by secreting ...

Pathophysiology bridges the gap between basic science and clinical care by explaining how diseases alter normal body functions. It reveals the causes, mechanisms, and progression of illness, helping ...

You might associate autoimmune conditions with symptoms like skin disease, chronic pain, and fatigue. But autoimmune disease hair loss can also happen. Your immune system is meant to keep you healthy ...