Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors. Its dose–response relationships with respect to side effects ...

When a randomized evaluation finds null results, it is important to understand why. We investigated two very different explanations for the finding from a randomized evaluation that the Camden ...

Following the frequent suspicions regarding the safety of cholesterol-lowering drugs in the pre-statin era,1 statins have been a recurrent object of various concerns and alarming news. For example, ...

Personalized Chemotherapy on the Basis of Tumor Marker Decline in Poor-Prognosis Germ-Cell Tumors: Updated Analysis of the GETUG-13 Phase III Trial Earlier detection of cancer offers an opportunity to ...

We conducted a phase 3, double-blind, double-dummy, randomized, controlled trial involving adults with acute, nonarteritic central retinal artery occlusion who had symptom onset within 4.5 hours ...

Results of a multisite randomized trial of Bright IDEAS-Young Adults: Efficacy of problem-solving skills training on distress and health-related quality of life. This is an ASCO Meeting Abstract from ...

A major Cochrane review examines whether a widely used herbal supplement truly supports cognitive function, revealing modest dementia benefits but limited evidence for prevention or early impairment.

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise ...

Pharmacologic options for essential tremor lack sufficient evidence for tremor reduction in trials with longer follow-up durations.