Inspired by the natural bonding between a class of potent local anesthetics called site-1 sodium channel blockers (S1SCBs) and peptide sequences on the sodium channel in the nerve cell membrane, ...

Advocates urge clinicians to consult with elective surgery patients about local anesthetics shortages, the potential health risks, and alternative forms of pain management. A global shortage of local ...

The FDA has notified healthcare professionals of 35 reports of chondrolysis in patients given continuous intra-articular infusions of local anesthetics (eg, bupivacaine, chlorprocaine, lidocaine, ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

What's the maximum recommended dose for lidocaine or mepivacaine during dental procedures? The answer remains unclear as guidelines published by dental organizations differ from those of manufacturers ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

A liposomal formulation of a local anesthetic shows promise for long-lasting pain relief with minimal toxicity, reports a research group led by Daniel S. Kohane of Harvard Medical School (Proc. Natl.

Lidocaine and similar local anesthetics are effective for treating pain that emanates from damaged nerves, according to a systematic review of current evidence. Lidocaine and similar local anesthetics ...

This medication is a local anesthetic, used in ophthalmology to determine fluid pressure inside the eye and for fitting of contact lenses. This medication is a local anesthetic used to treat painful ...

There is a real need in the treatment of postoperative pain and in the management of problems of intractable pain for local anesthetics with a duration of action longer than six to eight hours, the ...